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it. thank you so much. julia boorstin in l.a. >>> the placebo effect seems to be getting stronger. this is what we've been talking about, teasing throughout the show. many new drugs are failing in late stage trials because they can't actually beat out sugar pills. in fact, roughly half of them, according to this month's "
wired"
magazine which uncovers the fpharma cris. joing us, requested
wired"
magazine contributor steve silverman and erica schwartz. great to see both of you. a fascinating topic here. you say, actually, steve, half of all drugs in late-stage trials actually failed because they can't beat out the sugar pill equivalent, the placebo equivalent. how big a problem is this or could this become for the big pharma industry? >> well, it's a huge problem. because it costs, as you know, hundreds of millions of dollars to develop new drugs. and what's beating them in clinical trials is not actually a sugar pill, obviously, but it's the body's response to the act of taking a bill. which boosts up a lot of self-healing networks in the body that create real healing for things like depression, chronic pain, even parkinson's disease. so the placebo effect is not just a psychological phenomenon of thinks that you're getting better. people in clinical trials who take placebos actually do experience a lot of improvement in their health. this has become a serious problem for the companies. >> does this really show us the power of the mind and just exactly what it can do? >> absolutely. you know what's surprising? that it's taken so long. that you know what? if you think about it, the power of the mind, i mean, who we are, the body heals itself. and why is it that we don't look at that when we look at the placebo trials. the people get the drugs, the placebo, meaning care, do better. why is that so surprising? why have we been hiding it from the public for so long. >> steve silverman, just to pick up on that, i
read your entire piece last night and loved it. heck of a great piece of work. >> thank you. >> let me ask you abouterica schwartz's point. you know, you talk about the brain producing analgesics. you talk about one of the important transmitter, dopamine. why can't the pharmaceuticals harness these natural brain functions? >> you don't expect the drug company to harness the placebo effect, because they may have a hard time marketing sugar pills. who does need to harness it is the health care industry and doctors. drug companies for years have been burying clinical trials in which there was a high placebo response. because those are the studies that don't get them fda approval. >> erica take a whack at this very important point. we are learning these powerful, natural responses from our brain. which is a terrific thing. and it's got to be better than being on drugs all the time. >> absolutely. >> how can this be harnessed to help people? >> it's about the doctor-patient relationship. it's about traing doctors to really relate to the patient, to communicate with the patient. and you know what? it's great when a doctor is great at taking out a tumor. but we say, you know what? if the doctor takes out the tumor, that's good enough. the bedside manner doesn't matter. here's the proof that it matters. the only thing that matters is the bedside manner. then if the drug works that's great. >> erica, it's not -- that's sort of the bedside manner and the communication, very important. but how can the big pharma industry actually, larry's saying, really chemically take these natural endor fins that we have in our body and make them into products so that those can work. >> it can't. that's why they've been trying to hide it from us. because they can't. it's about you. how you feel. how you respond. when somebody tells you you're feeling great, if i gi you this you're going to feel better, you will feel better. >> what does it mean, erica, for big pharma going forward? >> they have to redefine what they're standing for and stop hiding the information. and you know what? as silverman said, the big pharma used to look at it as, you know, fake science, placebo effect. now it's the elephant in the board room. >> just on the way out, trish started with this and i think it's really the key stock market point. how damaging is this to the drug industry? >> it's very damaging. half the drugs that drop out of the pipeline now are dropping out because they can't beat placebo. but the real scoop in my article in a sense is that companies like merck, pfizer, lily, johnson and johnson now have an under the radar secret data sharing project to figure out what's going on with the placebo effect. they're keeping this quiet. it's been run through the nih. they're for the first timesharing their data from clinical trials to find out why the placebo effect seems to be rising worldwide. >> great stuff, guys. thank you. fascinating discussion. fascinating article. appreciate it. >>> up next, the health care debate flying under the radar. >> will immigration derail health care reform? as though it didn't have enough trouble, our next two guests face off in the call of the wild. reading about washington these days... i gotta ask, what's in it for me? i'm not looking for a bailout, just a good paying job. that's why i like this clean energy idea. now that works for our whole family. for the kids, a better environment. for my wife, who commutes, no more gettin' jerked around on gas prices... and for me, well, it wouldn't be so bad if this breadwinner brought home a little more bread. repower america. i hope our senators are listening. >>> welcome back.
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personal opinions and should be regarded as fact the court said was that there was specific evidence that this one person may have wide or another person in that circumstance we're going to disclose that made a noble says it complies with a court order saying we have legal team whose job it is to scrutinise these requests and make sure they need not only the letter but the spirit of the law . ford still says schools should have kept turning private and plan on suing mobil for 15 million dollars collins' attorney says he can't believe portion there . her being a victim here i have a i have trouble understanding that ... in this and hired a web watchers like
wired
magazine is nicholas thompson is a this is a lesson for all anonymous walkers some of the effect will be good people recognised with the 2nd the law does apply for the bodies their son will be back of the people who won't publish things that immediately should . for deciding force attorney says his client should have had a chance to appeal the judge's decision before information about her identity was revealed collins' attorney says much of this could have been avoided if or at simply apologised for what she had our jason carroll cnn new york . ... cnn will be sure before this case and they're progressives are for dot com gets hundreds of thousands of used each day to take a look right now some of the most popular videos list possibly . ... ... ... ... ... ...
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of chocolate finds that a brisk walk can reduce their craving. jessica -- >> i guess i got a lot of walking to do! thanks, lauren. it was started for college students. but now, more than 100 million "friends" of all ages are connected on facebook. with millions more on myspace and other social networks, our personal lives are intersecting around the world. and as hannah reports, that means using caution online is more important than ever. >> reporter: it's our choice what we put on these websites, but that choice can leave us open to strangers, and some sticky situations. once you have a facebook or myspace, it's kind of an agreement that people are going to talk about you and that you're gonna give people something to talk about. but you can control just how many people have that privilege. nicholas thompson is senior editor at "
wired"
magazine. here's a rule he says all teens should live by. >> never ever, absolutely never, zero times, nil, friend somebody you don't know. just don't ever do it. >> i only friend people who go to my school, or people i know through other friends. >> that's a great policy. and if you're feeling the itch to get out of your immediate circle, facebook helps you find "friends of friends", without jeopardizing your privacy. >> for example, let's say you went to school with a whole bunch of people, and you're friends with some of them. they're also probably likely friends with somebody else in that school, who you may have forgotten or you may not have had in your address book. so it's a good way to reconnect with people you've lost but who are also connected to your social network. and a good way to avoid strangers. >> mine's pretty private, more private than most people i know. >> these sites make it possible to be private. but you have to do the work. otherwise everyone in the world may be able to see your page. it happened to levi johnston. apparently he didn't take the time to make those few extra clicks. during the 2008 presidential campaign, when the media learned he was engaged to the daughter of alaska governor sarah palin, his myspace page went very public. so here's a guy who created his own page, he's 17 years old, thinks it's totally private, and you know, on monday, there are probably ten people who look at it, and on tuesday, probably 25 million. >> it can happen to the best of us. >> well, i kinda put something on facebook that was about my friend that wasn't exactly true, but i kinda heard it from another friend. but i didn't say that. so i kinda got in trouble for it and now i'm not friends with that person anymore. >> these are the uncool consequences of thinking anything is cool because we're in control of our pcs. >> a lot of times we get behind the computer and we're like, "ha, i'm behind the computer i can do whatever i want, type whatever i want, i'm gonna go crazy!" it's not a good idea. >> when it comes to posting online, the bottom line is "less is more." one of the rules that you should remember when you're facebook or when you're on myspace is don't say anything about anyone that you wouldn't say in public. >> rember it doesn't take much effort for a teacher, or the parents you babysit for, or that cute girl from your science class, to check out your wall. even your mom can look in. >> well yeah, my mom knows i have a facebook, and she's seen it so, i sorta try and keep it, i don't know, clean i guess. >> assume that your parents are gonna be reading your facebook page, even if you've set your privacy settings, they can probably figure out how to
read it. >> basically it's a good idea to treat your facebook or myspace page like the loudspeaker at school. don't write anything you don't want the whole world to hear played on full volume. for "teen kids news," i'm hannah. >> just ahead -- families helping kids get a healthy dose of fresh air. >> we'll be right back! matching makeup... begins with a weightless foundation that starts off white... and self-adjusts to precisely match your skin tone. with soft, flawless coverage. how cool is that? revlon skin matching makeup. >>> now, here's a story about
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aid and prevent the agony praised by the cans and other parents at this point to nick thompson is in new york is on the make ... getting the world panelists that senior editor of
wired
magazine the technology is certainly is it's it's in line is it is a chip implant effectively that work and reno and welcome back . think that's really worked when you did you have a chip implanted but the problem is that in order for it to really broadcasting location and it needs to have power enemies in implant a battery so you can use it in have a chip implanted that you can intervene but with this device if you're very close to it but that's not going to do any different adopted child in order . an abducted child what you need is implanted is and then you also need to have some signalling things and he signal as a battered currency also have to carry a watcher fanny pack or something that no one would never carry itself this doesn't really exist . ... ... and our tracking devices on the market right now and there is no doubt ones in there ... at times like these n e c's at a headline those cells and they is us . all sides but the idea volunteers whether it can actually work ultimately all not also raises questions of ethics of and charges that he said you i think overreaction and those charges coming from and no listen but not days . ... well what will head there is beginning in the future we're going to face very interesting that the devices when batteries have shrunken and that when the power there . i think the abilities of these kids had improved and that there may well be a point related interests in actual decision of when you have these in fact fearful that ... we're not there yet . what i suggest right now is the best thing you can actually if you can't if you were not businesses suffer because eight taking calls and instead the police on speed dialling and speed up entailed for short period bill ourself on their capital by the cell phone company itself it's actually a device that what nature can look we're on the playground and that you know there's a normal routine for charging or the plug in your arm or something else that strange and it actually works as effectively as almost anything else . our edge and ... . element is day in see the sort of tracking devices that we are talking back into myself but we although that can be tracked at this point and and make a very good point and it's very good piece of advice that more is it . ... i think there's quite a bit more to come there's a lot of work right now are in fact you are by egypt into animals for example and it's attracting animals not you know will not mean you can track in our id tag from an aeroplane you know that vienna was crossed into brazil or you can do is when you catch them or you can look at it you can see where it came from information will be embedded in itself there is a lot of work being down there but then again i mean the real
issue that has to be solved is the power problem . ... and when that
saw the 4th series of new avenues will open up and then with that bubbles there is a very complicated ethical questions . well having been given a charm as an internet the world panic out of your friends the night 7 8 colonels a pleasure thank you very likely that these women on this point releasing that pot use just then examined the model is no us .
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the senior editor of
wired
magazine whose article calls it a tragedy. harsh words. words. and david garrity, principal with gba research, who says come on, leave them alone. nick, let me ask you, i
read the article. i thought it was really interesting. the thing is that even though craigslist is really quirky it's really successful. >> oh, absolutely. craigslist is incredibly successful. and they're incredibly successful both from the number of users and from a financial perspective. they have 30 employees. they generate $100 million a year in revenue. that's insane. people in business schools will be stud them forever. what this article, written by gary wolfe, says is, look, there's an tount make craigslist so much better. the best real estate -- it's the most important real estate site we have. most important dating site. and yet it's a mess. you can't follow people. all this technology that's been built in the last ten years that makes so many other sites work better, craigslist says you know what, we kind of like things the way we are, we're not going to make it better. >> david, i mean, it's really plain and simple. craigslist is amazing. it has 30 employees, as opposed to ebay which has 16,000, amazon has 20,000, and yet craigslist has more traffic than both of them. is the secret to its success that it is so simple maybe? >> i think the fact that they -- the "
wired" article did a wonderful job in terms of going behind the site, talking about the dynamics of it. and it certainly kind of raised the
issue here in terms of a lot of things going on around craigslist they really can't be counted, they're not financial, that i non-measurable elements. and to the extent it's a very closely held company and to the extent that the model works for users, it's very difficult to see what the motivation might be for the people who own and control craigslist to really sort of prompt things to move further in the line of where the article wants the company to go. >> i mean, nick, the article makes the point, and you made the point -- you edited it, you didn't write that. sorry about that. but it makes the point that they're not monetizing this to the best of their ability. i mean, maybe the guy who found td doesn't want to. he makes that point in the article, you know, several times. craig newmark. that he really doesn't care about money. but you're saying obviously this could be an even much bigger business. >> but we're not talking about it from a business perspective. god bless craig newmark. in the story he says look, i have a nice apartment, i have a parking space, i have a shower with good water pressure. >> and he looks really cool and hip. >> why would i want -- the man is a billionaire and he cares about his shower's water pressure, not that his yacht is one foot bigger. so bless him. but the point is the site is a mess. there's spammers, scammers, all sorts of mayhem. this is a very important social link. you don't want to say social link for society, but it's a very important site for a lot of things that really matter to people, and there's a lot of technology out there that can make it way easier, way more useful, and it could do the things it does a lot better. one thing we did as a service, a free consulting service to craigslist-s we redesigned the site and we published it in craigslist and he with hope craig will look at it and say you know, what they're right. >> i don't think he's going to do that. david, i think nick is making the point that there have been the two so-called craigslist killers. there is all kinds of things going on in the site that are maybe not for the overall common-g although there's a lot of great things going on as well. i personally have sold a lot of furniture there. should they try and clean up their act a little more? >> from a quality standpoint there are always things that could be improved for all sites, and obviously craigslist is not exempt from that requirement. but at the same time if users were disaffected they wouldn't be having the traffic that they have. and they have been successful in terms of building a very, very substantial community as the "
wired" article spelled out. you mentioned the comparison earlier with ebay and amazon. if you looked at the productivity in craigslist in terms of a revenue per employee number, they're actually doing better than google by a factor of three times. the company is an amazing success. and from that standpoint until such point as the users come out and say look, it's broken, fix, it nothing's going to happen. >> yeah. and if you fix it it might dilute the brand a little. maybe people like it because it is so -- >> quirky. >> yes, exactly. thank you to both of you for joing us. that was fun. coming up, how to turn silver into gold. we're not talking about commodities.
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a judge ordered google reveal the name of the blogger who trashed the cover girl. she turned out to be this woman. see her there. 29-year-old rosemary port. she and her lawyer joined me last week. >> i was so grossly offended that i couldn't -- i couldn't do nothing. i wanted it gone and i didn't want to be there for the rest of my life. i knew the only way for it to be gone was to call my lawyer. >> defamation is not protected under the first amendment. second of all, she argued in court that there should be a lower standard. that basically this is trash talk and that it shouldn't be allowed because the overall context of the internet is trash talk. and the judge clearly rejected that and made a very strong statement that basically the internet's not going to be a safe harbor for defamatory language. >> well, now the blogger in question here is turning around and suing google to the tune of $15 million. she declined our request that she appear on the show tonight. her attorney is joining us along with nick thompson, the senior editor of "
wired"
magazine and back with us, our senior analyst, jeff toobin as well. a lot of people say this case is cut and dry. google was ordered by a judge to release your client's name. they did. end of story. >> it's easy to say that. when it comes to someone's right of privacy, i believe google should have fought harder to frequent my client's rights. >> it's not about privacy, is it? it's about defamation. >> it's about privacy. if you choose to be nopanonymous, the court and google should have protected my client's right to the fullest extent of the law. they did not do enough. the question is why. the local mom and pop shop that sells a book affords its customers more protection than this multibillion conglomerate afforded my client. as a matter of fact, campbell, their only defense was, well, if you get a court order we're going to have to turn it over. never arguing context, never arguing opinion, never formulating a correct offense for my client's due process rights. at the end of the day, they didn't even bother to give my client ample opportunity to appeal the decision. >> all right, jeff -- >> i just don't know where you get the right? do you have a contract with google? where's -- where do you get off saying that google is supposed to do something for your client when your client has done nothing but apparently defame another person using a fake name? >> well, your question is taken -- the very exact reason why they didn't give my client the right here. they didn't give my client an opportunity, a 36-hour window to appeal. this wasn't -- >> i don't understand -- why does google have to defend your client at all, for instance? >> because they said that they would. they had attorneys in court. i don't believe that they did the proper defense of my client's rights. this wasn't a criminal case. this wasn't a death penalty case. jeff, you know that it wasn't an immediate emergency here that google had to reveal her name so quickly. attorneys know every day they don't have to abide by a court order. they can walk across the street -- they could walk across the street and file an ae peel. >> let me bring nick into this. with all due respect it's about more than your case. my question is, there are a lot of websites out there, a lot of blogs that say really nasty stuff and are really mean. you know, as was alleged of his client. why target this young woman and her? is it just because she -- the person she was targeting sued? >> that's exactly why this one has come out into the public now. this comes out a lot. the big question, there's a very interesting point you two are making here. there are certainly cases where we would want google to fight on behalf of the people trying to be exposed by other people in court cases. >> whistle blowers, for instance. >> the iranian government said, you violated our laws. google give up your name. you would want google to fight with everything they have. should google go to the map and do all that in this particular case where it's one person writing comments on a blog? >> that's why she has me now. google wasn't able to afford my client the right protection. they didn't file a memorandum of law and opposition to the request. they did not do anything to protect my client's rights. >> very quickly. we're out of time. >> the next day it's going to be your rights. >> that's the problem here is that there are certain circumstances where we will care about internet protection. whistle blowers, political activists, but in this circumstance you don't -- it doesn't seem like you have a very sympathetic client. >> it's not for google to decide who should get what rights. my client is a citizen of the united states. >> a fair point. >> she should be afforded her points through due process. no one should decide who gets those rights or not other than an appellate division court. or the court of appeals. >> sal, we'll be very interested to see where your case goes. it is about much bigger
issues. appreciate your time. everyone's time. we have to end it there. thanks, guys. >>> take a look at this. it's a picture that rocked the modeling world. in a moment we're going to meet the model who is changing the shape of fashion. on. - enough! you get half and you get half. ( chirp ) team three, boathouse? ( chirp ) oh yeah-- his and hers. - ( crowd gasping ) - ( chirp ) van gogh? ( chirp ) even steven. - ( chirp ) mansion. - ( chirp ) good to go. ( grunts ) timber! ( chirp ) boss? what do we do with the shih-tzu? - ( crowd gasps ) - ( chirp ) joint custody. - phew! - announcer: get work done now. communicate in less than a second with nextel direct connect. only on the now network. deaf, hard of hearing and
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| Total Number of Clips: 6 | Cumulative Est. Audience: 1,187,383 |
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